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optic_nerve_hypoplasia [2025/02/20 23:20] – Scott Larsonoptic_nerve_hypoplasia [2026/08/08 23:26] (current) – Scott Larson
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 ====== Optic Nerve Hypoplasia ====== ====== Optic Nerve Hypoplasia ======
 +
 +FIXME links
   * Abnormally small optic nerve head   * Abnormally small optic nerve head
   * Congenital decrease optic nerve fibers   * Congenital decrease optic nerve fibers
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      * Ratio of Mean Disc Diameter (DD) to Macula-Disc distance (DM)      * Ratio of Mean Disc Diameter (DD) to Macula-Disc distance (DM)
        * (Horizontal + Vertical Disc Diameter /2) : Distance from center of disc to the center of the macula        * (Horizontal + Vertical Disc Diameter /2) : Distance from center of disc to the center of the macula
-       * {{::dd-dm_ratio.png?600|DD:DM ratio measurements}}\\ from Dutton GN. Congenital Disorders of the optic nerve: excavations and hypoplasia. Eye.2004;18:1038-1048+       * {{::dd-dm_ratio.jpg?600|DD:DM ratio measurements}}\\ from Dutton GN. Congenital Disorders of the optic nerve: excavations and hypoplasia. Eye.2004;18:1038-1048
      * OPTOS photographs of 188 adults and children with OHN (108) compared to normals (88)      * OPTOS photographs of 188 adults and children with OHN (108) compared to normals (88)
        * Normal optic nerve horizontal diameter: 1.70 mm (95% CI 1.49, 2.14)        * Normal optic nerve horizontal diameter: 1.70 mm (95% CI 1.49, 2.14)
        * Hypoplasia horizontal optic nerve diameter: 1.23 mm (95% CI 0.38, 1.45)        * Hypoplasia horizontal optic nerve diameter: 1.23 mm (95% CI 0.38, 1.45)
-       * {{::direct_optos_nerve_size_in_optic_nerve_hypoplasia_in_alaska_2020.pdf |Arnold AW et al. Direct OPTOS Nerve Size Determination of Prevalent Optic Nerve Hypoplasia in Alaska. Clinical Ophthalmology 2020;14:491-499}}+       * [[https://1drv.ms/b/c/31d83ae8e55e0542/ESt_2Vue-oRMuDq8pKqJrdEBpLHeUPKemCnXeNISNjZA0w?e=bKhGI1|Arnold AW et al. Direct OPTOS Nerve Size Determination of Prevalent Optic Nerve Hypoplasia in Alaska. Clinical Ophthalmology 2020;14:491-499]]
      * Optical Coherence Tomography      * Optical Coherence Tomography
 +       * Hypoplasia may be present the disc area is **<1.3 mm²**
        * Many commercial devices will attempt to plot the disc diameter and area         * Many commercial devices will attempt to plot the disc diameter and area 
-       * [[optic_disc_area_calculator|Use this calculator to estimate the nerve area using the Heidelberg OCT machine optic nerve report without the glaucoma upgrade]] +       * [[optic_disc_area_calculator|Optic Disc Area Calculator]] 
-       * [[optic_disc_area|Normal Values for Optic discs measured by OCT]]+       * [[optic_disc_area|Normal values for optic discs measured by OCT]]
    * MRI    * MRI
  
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     * diabetes insipidus     * diabetes insipidus
   * olfactory hypoplasia   * olfactory hypoplasia
-===In Olmstead County, MD population===+===In Olmstead County, MN population===
   * Premature birth- 32%   * Premature birth- 32%
   * Maternal diabetes- 16%   * Maternal diabetes- 16%
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 ======Resources====== ======Resources======
-  * {{::incidence_and_associated_endocrine_and_neurologic_abnormalities_of_optic_nerve_hypoplasia_2013.pdf |Mohoney BG et al. Incidence and Associated Endocrine and Neurologic Abnormalities of Optic Nerve Hypoplasia. JAMA Ophthalmol. 2013:131(7)898-902. }} +  * [[https://1drv.ms/b/c/31d83ae8e55e0542/EXou7apq3NFOlZH04pdLPqQBpiYNlBt9S-WmVznFg1SnYQ?e=j3DcTE |Mohoney BG et al. Incidence and Associated Endocrine and Neurologic Abnormalities of Optic Nerve Hypoplasia. JAMA Ophthalmol. 2013:131(7)898-902. ]] 
-  * {{:congentital_disorders_optic_nerve_excavations_copy.pdf|Dutton GN. Disorders of the optic nerve: excavations and hypoplasia.Eye 2004;18:1038-1048}} +  * [[https://1drv.ms/b/c/31d83ae8e55e0542/EbALeTleMYRGqziAQkiDphgB1fZLJ4kUM1l4z6GoJm9oyQ?e=zTQe6k|Dutton GN. Disorders of the optic nerve: excavations and hypoplasia.Eye 2004;18:1038-1048]] 
-  * {{::direct_optos_nerve_size_in_optic_nerve_hypoplasia_in_alaska_2020.pdf |Arnold AW et al. Direct OPTOS Nerve Size Determination of Prevalent Optic Nerve Hypoplasia in Alaska. Clinical Ophthalmology 2020;14:491-499}} +  * [[https://1drv.ms/b/c/31d83ae8e55e0542/ESt_2Vue-oRMuDq8pKqJrdEBpLHeUPKemCnXeNISNjZA0w?e=A619Fu |Arnold AW et al. Direct OPTOS Nerve Size Determination of Prevalent Optic Nerve Hypoplasia in Alaska. Clinical Ophthalmology 2020;14:491-499]] 
-  * {{::comparison_of_heidelberg_retina_tomograph_with_disc-macula_distance_to_disc_2016.pdf |Pang Y. et al. Comparison of Heidelberg Retina Tomograph with disc macula distance to disc diameter ratio in diagnosing optic nerve hypoplasia}} +  * [[https://1drv.ms/b/c/31d83ae8e55e0542/EQXHTUG146BNjm-6aMvfF_4BCx_ZOyFj_AXFPbXxYowuuw?e=o5KXUa |Pang Y. et al. Comparison of Heidelberg Retina Tomograph with disc macula distance to disc diameter ratio in diagnosing optic nerve hypoplasia]] 
-  * {{::clinical_and_morphologic_spectrum_of_optic_nerve_hypoplasia_1999.pdf |Hellström A. et al. The Clinical and Morphologic Spectrum of Optic Nerve Hypoplasia. JAAPOS 1999;3(4):212-20}}+  * [[https://1drv.ms/b/c/31d83ae8e55e0542/EUP2UMLDXHRDk-qp6d_7bF8BHBrRvLUVy8jVVt2ljf9tLw?e=UDqUYw |Hellström A. et al. The Clinical and Morphologic Spectrum of Optic Nerve Hypoplasia. JAAPOS 1999;3(4):212-20]]
  
 {{tag>optic_disc}} {{tag>optic_disc}}