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nanophthalmia [2026/07/27 11:16] – [Treatment] Scott Larsonnanophthalmia [2026/07/27 12:08] (current) – Scott Larson
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 ===== Definition ===== ===== Definition =====
  
-Nanophthalmos is a rare developmental ocular disorder characterised by a small but structurally normal eye with a significantly shortened axial length (typically ≤20.5–21.0 mm; mean ~17.6–18.1 mm), high hyperopia (often +7 to +13 diopters), a high lens-to-eye volume ratio, shallow anterior chamber, thickened sclera, and small cornea. It represents the extreme end of the hyperopia spectrum and is distinct from microphthalmos, which involves structural ocular abnormalities.+  * Small but largely structurally normal eye 
 +  * Characterized by: 
 +    * Significantly shortened axial length (typically ≤20.5–21.0 mm; mean ~17.6–18.1 mm) 
 +    * [[high_hyperopia|High hyperopia]] (often +7 to +13 diopters),  
 +    * High lens-to-eye volume ratio 
 +    * Shallow anterior chamber 
 +    * Thickened sclera 
 +    * Small cornea.  
 +  * Distinct from [[microphthalmos|microphthalmos]], which involves structural ocular abnormalities.
  
 ===== Potential Causes / Genetics ===== ===== Potential Causes / Genetics =====