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| microphthalmos [2026/07/27 12:05] – Scott Larson | microphthalmos [2026/07/27 12:06] (current) – [Definition] Scott Larson | ||
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| ===== Definition ===== | ===== Definition ===== | ||
| - | **Microphthalmos** (also spelled | + | **Microphthalmos** (or microphthalmia) is a congenital eye malformation characterized by a **reduction in the volume of the eye** |
| * Corneal diameter typically < 10 mm | * Corneal diameter typically < 10 mm | ||
| * Anteroposterior globe diameter less than 20 mm (or an axial length below 2 standard deviations for chronological age).[1][2] | * Anteroposterior globe diameter less than 20 mm (or an axial length below 2 standard deviations for chronological age).[1][2] | ||
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| * Microphthalmia reported in up to 11% of blind children.[5] | * Microphthalmia reported in up to 11% of blind children.[5] | ||
| * Isolated (nonsyndromic) 66% | * Isolated (nonsyndromic) 66% | ||
| - | * Part of a broader syndrome (syndromic) | + | * Part of a broader syndrome (syndromic) 33%.[3][5] |
| ===== Associated Conditions ===== | ===== Associated Conditions ===== | ||