Differences

This shows you the differences between two versions of the page.

Link to this comparison view

Both sides previous revision Previous revision
Next revision		 Previous revision
blepharokeratoconjunctitis [2025/11/02 13:44] – Scott Larsonblepharokeratoconjunctitis [2026/09/16 08:34] (current) – [Treatment] Scott Larson
Line 7: Line 7:
 ====Risk Factors==== ====Risk Factors====
   * Poor hygiene   * Poor hygiene
-  * Seborrheic dermatitis +  * [[seborrheic_dermatitis|Seborrheic dermatitis]] 
-  * History of Atopy +  * History of [[atopy|Atopy]]- predisposition to produce IgE in response to common allergens 
   * Infestation with Demodex mites   * Infestation with Demodex mites
   * High levels of C.acnes bacteria in meibum cultures   * High levels of C.acnes bacteria in meibum cultures
Line 18: Line 18:
 ====Treatment==== ====Treatment====
 ===Bacteria=== ===Bacteria===
-  * [[azythromycin|Azithromycin]] 
-    * PO 250-500 mg thrice weekly for 4-8 weeks (5-10 mg/kg)   
-    * Topical: Azasite 1% ophthalmic solution most useful in maintenance of remission 
   * Erythromycin    * Erythromycin 
-    * PO 250-500 mg QD or BID x 4-8 weeks +    * Topical: 0.5% ointment, most helpful for maintaining remission  
-    * Topical: 0.5% ointment, most helpful for maintaining remission   +
-  * [[doxycycline|Doxycycline]] in children over 8 with their adult teeth.     +
-    * Low dose:  40 mg QD or 20 mg BID x 4-8 weeks  +
-    * Regular dose: 100 mg QD x 4-8 weeks+
 ===Demodex=== ===Demodex===
   * Tea Tree Oil 50% eyelid scrubs daily   * Tea Tree Oil 50% eyelid scrubs daily
Line 32: Line 26:
   * [[https://xdemvyhcp.com |Xdemvy drops (lotilaner ophthalmic solution 0.25%)]] BID x 6 weeks   * [[https://xdemvyhcp.com |Xdemvy drops (lotilaner ophthalmic solution 0.25%)]] BID x 6 weeks
     * Send to BlinkRx  Phone: 1-833-919-4942 Fax: 1-866-585-4631 12639 W Explorer Dr, Suite 100 Boise, ID 83713  NPI #: 1891461885     * Send to BlinkRx  Phone: 1-833-919-4942 Fax: 1-866-585-4631 12639 W Explorer Dr, Suite 100 Boise, ID 83713  NPI #: 1891461885
 +===Meibomian Gland Dysfunction===
 +  * Flaxseed oil- 1 Tsp/day = about 1800 ALA,  or 2 capsule about 720 ALA/capsule
 +  * Azithromycin (preferred over erythromycin—better bioavailability, longer half-life, higher tissue concentration)
 +    * 5 mg/kg daily for 2 months 
 +    * Pulsed/cyclic 5-7 day course,  one week on 3 week off
 +    * Monitor for GI upset and QT prolongation.
 +  * Topical: Azasite 1% ophthalmic solution most useful in maintenance of remission
 +  * [[doxycycline|Doxycycline]] only in children over 8 with their adult teeth.    
 +    * Low dose:  40 mg QD or 20 mg BID x 4-8 weeks 
 +    * Regular dose: 100 mg QD x 4-8 weeks