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| behcet_disease [2026/02/04 22:43] – [Etiology] Scott Larson | behcet_disease [2026/02/04 22:46] (current) – [Etiology] Scott Larson | ||
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| ====== Behçet' | ====== Behçet' | ||
| - | FIXME | + | |
| ====Main Features==== | ====Main Features==== | ||
| * Systemic Vasculitis characterized by recurrent oral ulcers (nearly all) with variable involvement of skin, eyes, joints, vascular system, GI tract and CNS | * Systemic Vasculitis characterized by recurrent oral ulcers (nearly all) with variable involvement of skin, eyes, joints, vascular system, GI tract and CNS | ||
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| ====Etiology==== | ====Etiology==== | ||
| * Genetically predisposed are exposed to environmental triggers leading to activation of cellular signally pathways leading to tissue inflammation and damage. | * Genetically predisposed are exposed to environmental triggers leading to activation of cellular signally pathways leading to tissue inflammation and damage. | ||
| - | * HLA B51 increases the risk by 6 | + | * HLA B*51 increases the risk by 6 |
| * Highest prevalence in Turkey: 420 cases per 100,000 | * Highest prevalence in Turkey: 420 cases per 100,000 | ||
| * US: 5.2 cases per 100, | * US: 5.2 cases per 100, | ||